• Discover the emerging concept of the brain pathobiome and how microbes, the immune system, and the brain may interact throughout life.

  • Explore the latest evidence linking infections and host immune responses to Alzheimer's disease, Parkinson's disease, PANS/PANDAS, and psychiatric disorders.

  • Learn how advances in neuropathology, molecular diagnostics, genomics, and biomarker discovery are transforming our understanding of brain disease.

  • Examine the biological mechanisms through which pathogens, inflammation, vascular dysfunction, and immune dysregulation may contribute to neurological disease.

  • Gain insights into innovative experimental models and translational research that are advancing new approaches to diagnosis, prevention, and treatment.

  • Hear directly from NIH leaders, practicing clinicians and internationally recognized scientists about emerging research priorities, collaborative initiatives, and future funding opportunities.

  • Understand how multidisciplinary collaboration is accelerating discoveries by integrating neuroscience, infectious diseases, immunology, psychiatry, pathology, precision medicine, and beyond.

  • Explore a new framework for brain health and disease that challenges traditional silos and encourages innovative approaches to understanding complex neurological and psychiatric conditions across the human lifespan.